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Offline stack

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Re: Cancer is easily cured with common grocery store items
« Reply #260 on: July 07, 2019, 11:28:34 PM »
The study you cited is a totally different study with different doses and cancers and timespans.

The people in the study I cited were given the same treatment and their cancers were suppressed in a double-blind study against a control group. The control group without the high doses of garlic had cancers which proliferated. How did those people in that study taking high dose garlic coincidentally regress?

The quote provided from the paper I referenced is in regard to the study you originally referenced. Read it again.

But jesus, where are you going with all this? More research is required. The paper I referenced cited promising elements of AGE as a cancer inhibitor, but that many factors have not been controlled for in the human studies so it's efficacy is still unknown. I am not arguing that garlic may provide some health benefits. So may red wine and a Med diet for heart disease. But it's cavalier to be stating things like the title of this thread and "Garlic suppresses cancer in humans" when it's unclear and certainly undecided.

I'm all for the research, so it's great to dig these studies and such up and share, just don't go laying down absolutes where there aren't any. It's misleading. 
Not much is known about the celestial bodies and their distances.

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Offline markjo

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Re: Cancer is easily cured with common grocery store items
« Reply #261 on: July 08, 2019, 12:04:10 AM »
Garlic suppresses cancer in humans:

https://www.ncbi.nlm.nih.gov/pubmed/16484573

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Aged garlic extract has potential suppressive effect on colorectal adenomas in humans.
Tanaka S1, Haruma K, Yoshihara M, Kajiyama G, Kira K, Amagase H, Chayama K.

...

The results suggest AGE suppresses progression of colorectal adenomas in humans. It appears that AGE has multiple pathways to reduce cancer incidence and suppress its growth and proliferation.
Tom, if your own source won't say with certainty that AGE suppresses cancer, then you shouldn't either.
Abandon hope all ye who press enter here.

Science is what happens when preconception meets verification.

If you can't demonstrate it, then you shouldn't believe it.

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Offline BillO

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Re: Cancer is easily cured with common grocery store items
« Reply #262 on: July 22, 2019, 01:48:06 PM »
The study you cited is a totally different study with different doses and cancers and timespans.

The people in the study I cited were given the same treatment and their cancers were suppressed in a double-blind study against a control group. The control group without the high doses of garlic had cancers which proliferated. How did those people in that study taking high dose garlic coincidentally regress?

One study is just an indication and not a reason to claim anything.  There could have been other commonalities between those that enjoyed the cancer suppression.  A good result like this is certainly cause for further study though.   
Here a quack, there a quack, everywhere a quack quack.


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Offline Tom Bishop

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Re: Cancer is easily cured with common grocery store items
« Reply #264 on: August 26, 2019, 11:26:18 PM »
Here are some more coincidences:

https://europepmc.org/abstract/med/15726891

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A Garlic Derivative, S-allylcysteine (SAC), Suppresses Proliferation and Metastasis of Hepatocellular Carcinoma

Abstract

Background

Hepatocellular carcinoma (HCC) is highly malignant and metastatic. Currently, there is no effective chemotherapy for patients with advanced HCC leading to an urgent need to seek for novel therapeutic options. We aimed to investigate the effect of a garlic derivative, S-allylcysteine (SAC), on the proliferation and metastasis of HCC.

Methodology/Principal Findings

A series of in vitro experiments including MTT, colony-forming, wound-healing, invasion, apoptosis and cell cycle assays were performed to examine the anti-proliferative and anti-metastatic effects of SAC on a metastatic HCC cell line MHCC97L. The therapeutic values of SAC single and combined with cisplatin treatments were examined in an in vivo orthotopic xenograft liver tumor model. The result showed that the proliferation rate and colony-forming abilities of MHCC97L cells were suppressed by SAC together with significant suppression of the expressions of proliferation markers, Ki-67 and proliferating cell nuclear antigen (PCNA). Moreover, SAC hindered the migration and invasion of MHCC97L cells corresponding with up-regulation of E-cadherin and down-regulation of VEGF. Furthermore, SAC significantly induced apoptosis and necrosis of MHCC97L cells through suppressing Bcl-xL and Bcl-2 as well as activating caspase-3 and caspase-9. In addition, SAC could significantly induce the S phase arrest of MHCC97L cells together with down-regulation of cdc25c, cdc2 and cyclin B1. In vivo xenograft liver tumor model demonstrated that SAC single or combined with cisplatin treatment inhibited the progression and metastasis of HCC tumor.

Conclusions/Significance

Our data demonstrate the anti-proliferative and anti-metastatic effects of SAC on HCC cells and suggest that SAC may be a potential therapeutic agent for the treatment of HCC patients.

https://clincancerres.aacrjournals.org/content/13/6/1847.short

Quote
Garlic-Derived S-allylmercaptocysteine Is a Novel In vivo Antimetastatic Agent for Androgen-Independent Prostate Cancer

Abstract

Purpose: There is epidemiologic evidence that high garlic consumption decreases the incidence of prostate cancer, and compounds isolated from garlic have been shown to have cancer-preventive and tumor-suppressive effects. Recent in vitro studies in our laboratory have shown that garlic-derived organosulfur compound S-allylmercaptocysteine suppresses invasion and cell motility of androgen-independent prostate cancer cells via the up-regulation of cell-adhesion molecule E-cadherin. S-allylmercaptocysteine is therefore a potential antimetastatic drug with broad clinical applications that we tested in vivo for the first time in this study.

Experimental Design: We used a newly established fluorescent orthotopic androgen-independent prostate cancer mouse model to assess the ability of S-allylmercaptocysteine to inhibit tumor growth and dissemination.

Results: We showed that oral S-allylmercaptocysteine not only inhibited the growth of primary tumors by up to 71% (P < 0.001) but also reduced the number of lung and adrenal metastases by as much as 85.5% (P = 0.001) without causing notable toxicity. This metastatic suppression was accompanied by a 91% reduction of viable circulating tumor cells (P = 0.041), suggesting that S-allylmercaptocysteine prevents dissemination by decreasing tumor cell intravasation.

Conclusions: Our results provide in vivo evidence supporting the potential use of S-allylmercaptocysteine as an E-cadherin up-regulating antimetastatic agent for the treatment of androgen-independent prostate cancer. This is the first report of the in vivo antimetastatic properties of garlic, which may also apply to other cancer types.
« Last Edit: August 27, 2019, 08:02:35 AM by Tom Bishop »