The only advantage Goku has is his martial skills, but that won't help him when he's fighting someone who can take anything he can throw at him. Superman is stronger, faster, and he can go longer without rest. He could literally deflect Gokus most powerful Kamehameha or Genki Dama (didn't watch the dub, so I don't know what they call it there) with but a flick of his wrist. By then, Goku would be so exhausted he'd pass out.