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Philosophy, Religion & Society / Re: Died Suddenly
« on: December 26, 2022, 08:33:57 AM »
Pfizer knew from the start that Sars-Cov-2 is a mycobacterium:
https://www.clinicaltrialsarena.com/news/pfizer-data-azithromycin-covid-19-trial/
The Sars-Cov-2 genome has sequences from the following pathogenic agents:
Mycobacterium tuberculosis, Mycobacterium leprae, Bacillus anthracis, Borrelia burgdorferi, Clostridium perfringens, Clostridium tetani, Helicobacter Pylori, Listeria monocytogenes, Staphylococcus aureus, Streptococcus pyogenes, Vibrio cholera and Yersinia pestis), two malarial parasites (Plasmodium falciparum and Plasmodium knowlesi) and influenza virus A.
https://www.sciencedirect.com/science/article/pii/S0171298521000395
Monkeypox (MPV) is actually mousepox, and poxviridae is also a mycobacterium (a variant of M. leprae):
https://archive.org/details/b30503036/page/n34/mode/1up (pg 16-18)
MPV is related to Sars-Cov-2 through RNA G-quadruplex structures:
https://www.biorxiv.org/content/10.1101/2022.06.18.496696v1
Non-coding RNA and M. tuberculosis:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384566/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628891/
https://www.frontiersin.org/articles/10.3389/fcimb.2014.00096/full
Non-coding RNA and prions:
https://www.researchgate.net/publication/326183713_Interrelation_of_prions_with_non-coDing_RNAs
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333576/
https://pubmed.ncbi.nlm.nih.gov/34209482/
https://rupress.org/jcb/article/210/4/529/38290/Prion-like-domains-in-RNA-binding-proteins-are
G-quadruplexes and prions:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132711/
The above data demonstrate that sequences within PrP mRNA have the propensity to switch between hairpin structures and G-quadruplexes depending on environmental conditions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314185/
https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(20)30272-3
G-Quadruplexes in RNA Biology: Recent Advances and Future Directions
Other indirect but promising pieces of evidence support that RG4s might be part of the structural ‘switch’ induced by the pseudouridylation of tRNA-derived fragments important for translation initiation impacting stem cell commitment during key developmental processes.
Omicron (Mers-Cov-2) is activating its prion domain (example, the CH.1.1 variant, with the P681R mutation).
https://rense.com/general96/K-20220328/CREUTZFELDT-JACOB%20SARS-COV-2.pdf
The Mers-Cov-2 and Sars-Cov-2 spike protein has a similar structure:
Here we report that among spike protein sequences of genus Betacoronavirus and outside of the SARS-CoV-2 clade an analogous polyfunctional domain was found in only one other virus: an artificial MERS infectious clone, described already in 2017, which constitutes an adapted genotype from serial passage in genetically humanized mice. In contrast to this artificial MERS coronavirus, which has no natural primary host and which during passage acquired the full pat7 motif, S protein sequences from all other betacoronaviruses did not present a polyfunctional S1/S2 junction domain analogous to SARS-CoV-2. As the evolutionarily closest betacoronaviruses outside of the SARS-CoV-2 clade lack all its three functional features, this critical S1/S2 polyfunctional domain becomes an unlikely product of natural evolution alone.
https://web.archive.org/web/20221214164619/https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4301576
https://www.clinicaltrialsarena.com/news/pfizer-data-azithromycin-covid-19-trial/
The Sars-Cov-2 genome has sequences from the following pathogenic agents:
Mycobacterium tuberculosis, Mycobacterium leprae, Bacillus anthracis, Borrelia burgdorferi, Clostridium perfringens, Clostridium tetani, Helicobacter Pylori, Listeria monocytogenes, Staphylococcus aureus, Streptococcus pyogenes, Vibrio cholera and Yersinia pestis), two malarial parasites (Plasmodium falciparum and Plasmodium knowlesi) and influenza virus A.
https://www.sciencedirect.com/science/article/pii/S0171298521000395
Monkeypox (MPV) is actually mousepox, and poxviridae is also a mycobacterium (a variant of M. leprae):
https://archive.org/details/b30503036/page/n34/mode/1up (pg 16-18)
MPV is related to Sars-Cov-2 through RNA G-quadruplex structures:
https://www.biorxiv.org/content/10.1101/2022.06.18.496696v1
Non-coding RNA and M. tuberculosis:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384566/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628891/
https://www.frontiersin.org/articles/10.3389/fcimb.2014.00096/full
Non-coding RNA and prions:
https://www.researchgate.net/publication/326183713_Interrelation_of_prions_with_non-coDing_RNAs
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333576/
https://pubmed.ncbi.nlm.nih.gov/34209482/
https://rupress.org/jcb/article/210/4/529/38290/Prion-like-domains-in-RNA-binding-proteins-are
G-quadruplexes and prions:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132711/
The above data demonstrate that sequences within PrP mRNA have the propensity to switch between hairpin structures and G-quadruplexes depending on environmental conditions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314185/
https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(20)30272-3
G-Quadruplexes in RNA Biology: Recent Advances and Future Directions
Other indirect but promising pieces of evidence support that RG4s might be part of the structural ‘switch’ induced by the pseudouridylation of tRNA-derived fragments important for translation initiation impacting stem cell commitment during key developmental processes.
Omicron (Mers-Cov-2) is activating its prion domain (example, the CH.1.1 variant, with the P681R mutation).
https://rense.com/general96/K-20220328/CREUTZFELDT-JACOB%20SARS-COV-2.pdf
The Mers-Cov-2 and Sars-Cov-2 spike protein has a similar structure:
Here we report that among spike protein sequences of genus Betacoronavirus and outside of the SARS-CoV-2 clade an analogous polyfunctional domain was found in only one other virus: an artificial MERS infectious clone, described already in 2017, which constitutes an adapted genotype from serial passage in genetically humanized mice. In contrast to this artificial MERS coronavirus, which has no natural primary host and which during passage acquired the full pat7 motif, S protein sequences from all other betacoronaviruses did not present a polyfunctional S1/S2 junction domain analogous to SARS-CoV-2. As the evolutionarily closest betacoronaviruses outside of the SARS-CoV-2 clade lack all its three functional features, this critical S1/S2 polyfunctional domain becomes an unlikely product of natural evolution alone.
https://web.archive.org/web/20221214164619/https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4301576