There is an neat experiment that anyone can do in their livingroom. It demonstrates how easy it is for your brain to misinterpret reality.
What you need:
sunglasses lens
string
coin or small object to tie onto the string
Tie a small object such as a coin onto a string, and using a single lens from sunglasses, cover one of your eyes (only one). Now swing the pendulum from side to side in front of you. It's easier if you have someone else swing it while you watch.
You will notice the pendulum swinging circles, not merely side to side. Why is this?
Light slows down as it passes through a lens, so by the time it hits your eye, it is milliseconds slower than the light that hits your other eye. In order for your brain to interpret this mixed signal, you perceive the pendulum moving in a circles even though it is really moving side to side.
This demonstrates that your brain will create perception even in spite of reality.
P.S. - In light of this experiment, perhaps we shouldn't be talking about the "reliability of senses"... but rather we should be talking about the "reliability of perception"?